Individual

RC2 - Roller Coaster Session - RC2

Tuesday, October 21, 2025

10:45 AM - 12:15 PM MDT

Location: Willow Lake 3 - 5

Chair(s)

Disclosure(s):

Yi Ting (Kayla) Lien, PhD: No financial relationships to disclose

10:45 AM - 11:00 AM MDT

Unravelling the pharmacokinetics of oligonucleotides by using a PBPK model
Speaker: Felix Stader, PhD – Certara Predictive Technologies
11:00 AM - 11:15 AM MDT

A copula-based approach for generating realistic virtual patient populations in quantitative pharmacology
Speaker: Yuchen Guo, MSc – Leiden University
11:15 AM - 11:30 AM MDT

Will harmonization in guidance lead to consistency in assessment and regulatory decisions, with a focus on PBPK modeling in new drug approvals (NDAs) and marketing authorization applications (MAAs)?
Speaker: Xinyuan (Susie) Zhang, PhD – Simulations Plus
11:30 AM - 11:45 AM MDT

Hepatitis Viral Disease QSP Model Can Inform Efficacious Dose for Immunotherapy
Speaker: Meghna Verma, MS, PhD (she/her/hers) – AstraZeneca
11:45 AM - 12:00 PM MDT

12 years of modeling ADCs in oncology: lessons learned, insights gleaned, creativity unleashed
Speaker: Katharina Wilkins, PhD (she/her/hers) – Novartis