Sergey Aksenov, PhD

Sr Director Modeling Simulation
Arvinas
Lexington, Massachusetts, United States

Sergey Aksenov, a PhD in Physics from Moscow State University, is currently Head of Modeling and Simulation at Arvinas. He spearheads PKPD and pharmacometrics modeling for all PROTAC projects from discovery through confirmatory studies in neurology and oncology. His extensive experience includes translational and early-phase modeling for small molecules, biologics, and gene therapies at Novartis, and serving as Pharmacometrics Science Lead at AstraZeneca. Previously, he was a modeling and simulation scientist at Novartis, focusing on developing drug for neurology and ophthalmology diseases.

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Presentation(s):

• Design of a First-in-Human Study for ARV-102, a Brain-Penetrant PROteolysis TArgeting Chimera (PROTAC) LRRK2 Degrader, Using Pharmacokinetic (PK)-Pharmacodynamic (PD) Modeling

  Tuesday, October 21, 2025
  10:45 AM - 11:00 AM MDT