RC1 - Roller Coaster Session - RC1

Chair(s)

• 

  Joy Hsu, PhD (she/her/hers)

  Director, Clinical Pharmacology and Pharmacometrics
  Genentech, California, United States

Presentations:

• 10:45 AM - 11:00 AM MDT

  Design of a First-in-Human Study for ARV-102, a Brain-Penetrant PROteolysis TArgeting Chimera (PROTAC) LRRK2 Degrader, Using Pharmacokinetic (PK)-Pharmacodynamic (PD) Modeling
  

  Speaker: Sergey Aksenov, PhD – Arvinas
• 11:00 AM - 11:15 AM MDT

  Full Random Effects Modelling (FREM): Scaling the Heights of Covariate Modelling
  

  Speaker: E. Niclas Jonsson, PhD – Pharmetheus AB
• 11:15 AM - 11:30 AM MDT

  Pharmacometric methods used in the assessment of pulmonary drug deposition
  

  Chair: Celestine J. Rebello – Cipla Ltd
• 11:30 AM - 11:45 AM MDT

  Machine Learning Augmented Tumor Growth and Survival Models: Insights from Hepatocellular Carcinoma Data
  

  Speaker: Ahmed Elmokadem, PhD – Metrum Research Group