Professor University at Buffalo Buffalo, New York, United States
Disclosure(s):
Wojciech Krzyzanski, PhD: No financial relationships to disclose
The course will provide an overview of biological systems exhibiting delays, concepts of lifespan driven pharmacodynamic response, modelling of cell maturation, transduction delays, and nonlinear mixed-effect lifespan models. Delay differential equations (DDEs) will be introduced and implemented in NONMEM version 7.5. The course will consist of both lectures and hands-on computer exercises. Source codes for DDE based PK/PD models and data will be provided to the participants. For course information visit https://sites.google.com/site/delaysinpkpd