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ViewAttendees 8
Symposium

Big Data/AI/Machine Learning

C3B - Envisioning the Role of GenAI in Modern Pharmacometric Workflows

Monday, October 20, 2025
2:00 PM - 3:30 PM MDT
Location: Willow Lake 3 - 5

Disclosure(s):
Birgit Schoeberl, PhD: No relevant disclosure to display
Emily Nieves: No financial relationships to disclose
Joshua F. Apgar, PhD: No financial relationships to disclose

Description of session (include background & scientific importance): Large Language Models are transforming the process of how we conduct research. LLMs can process and analyze large amounts of scientific literature or integrate and interpret complex datasets and thus help in the generation of novel hypotheses.

In this session, we will present three examples, where GenAI is being applied to pharmacometric workflows from data preparation, the automation of repetitive workflows like applying different scaling methods to predict the human exposure of small molecules and to the concept of “AI pharmacometricians”.

Learning Objectives:

  • Upon completion, participant will be able to: identify valuable applications of GenAI in pharmacometric workflows, understand how to apply GenAI techniques, including advanced agentic architectures, in a scientifically rigorous way

Presentations:

  • 2:00 PM - 2:20 PM MDT
    Accelerate human exposure prediction with GenAI

    Speaker: Birgit Schoeberl, PhD (she/her/hers) – Novartis Institutes for BioMedical Research

  • 2:20 PM - 2:40 PM MDT
    Leveraging GenAI for the creation of fit-for-purpose datasets from literature

    Chair: Emily Nieves (she/her/hers) – Delineate Inc.

  • 2:40 PM - 3:00 PM MDT
    Quantitative Systems Pharmacology at Scale with Generative AI

    Speaker: Joshua F. Apgar, PhD (he/him/his) – Certara

  • 3:00 PM - 3:30 PM MDT
    Panel - Envisioning the Role of GenAI in Modern Pharmacometric Workflows

    Panelist: Birgit Schoeberl, PhD (she/her/hers) – Novartis Institutes for BioMedical Research

    Panelist: Emily Nieves (she/her/hers) – Delineate Inc.

    Panelist: Joshua F. Apgar, PhD (he/him/his) – Certara

    Panelist: Allison Claas, PhD (she/her/hers) – Novartis